Issam Awad

Preventing strokes and brain bleeds

In the newest episode of Inside the Lab, visit Issam Awad and learn about his team's mission: to prevent strokes before they happen.
READ MORE NEWS AT THE FOREFRONT AND SCIENCE LIFE
 
Brain maze
 

New rules for the game of memory

Mark Sheffield’s lab upends traditional views on synaptic plasticity.
T cells
 

Peacekeeper cells protect the body from autoimmunity

Pete Savage shows how “doppelganger” T cells help prevent autoimmunity.
Zebrafish DNA
 

DNA microscope creates 3D images from the inside out

Josh Weinstein created a spatial map of gene expression for an entire organism.

NEWS AND ANNOUNCEMENTS

Match Day students

Match Day 2025: Cheers, tears and a new record

A record-high 17% of this year's UChicago Pritzker School of Medicine graduates will pursue residencies in psychiatry.
 
 

Four postdoctoral scholars named 2025 Chicago Fellows

The highly competitive Chicago Fellows Program aims to support and shape new leaders in the biological and biomedical sciences.
 
 

Kunle Odunsi named speaker for UChicago’s 2025 Convocation ceremony

Odunsi, a gynecologic oncologist who specializes in the treatment of ovarian cancer, serves as the Director of the Comprehensive Cancer Center and is Dean for Oncology in the BSD.
 
 

HONORS AND ACCOLADES

Eugene Chang inducted into AIMBE College of Fellows

The American Institute for Medical and Biological Engineering (AIMBE) inducted Eugene B. Chang, Martin Boyer Distinguished Professor of Medicine, to its College of Fellows. Election to the AIMBE College of Fellows is among the highest professional distinctions accorded to medical and biological engineers. Chang was elected “for pioneering microbiome discoveries transforming understanding of host-microbe interactions and therapeutics in human health and disease.”
 
 

Pavitra Muralidhar receives Rosalind Franklin Young Investigator Award

Pavitra Muralidhar, Assistant Professor of Ecology and Evolution, was one of three recipients of the Rosalind Franklin Young Investigator Award from the Genetics Society of America and The Gruber Foundation. The award is granted once every three years to women who have conducted exceptionally original and creative research in the field of genetics and have recently begun an independent faculty-level position.
 
 

Betsy Cliff honored for health services research

Health Services Research selected an article by Betsy Cliff, Asst. Prof. Public Health Sciences, as this year's James F. Burgess Methods Article of the Year. The journal gives this award in honor of a former HSR senior associate editor to recognize excellent research in health services methods. Cliff’s paper was about creating a reliable health insurance variable in large datasets.
 
 

RESOURCES

2025 BSD Clinical Research Awards Nominations

Nominations for the 2025 BSD Clinical Research Awards are now open! Any faculty or staff person in the BSD or UCM may nominate staff and faculty for the awards. Nominations will close on May 2 and winners will be announced during Clinical Trials Day celebrations on May 21.
 
 

FEATURED EVENTS

 
Charles Swanton

Andros Lecture

Feat. Charles Swanton of the Francis Crick Institute
April 3
Chris Jewell

Materials to study immune function

Feat. Chris Jewell from Cartesian Therapeutics
April 8

Memorial and Reception for John Reinitz

April 9, Bond Chapel
 
 

LAB NOTEBOOK

More research publications and viewpoints from our faculty and trainees:
 
Safety and efficacy of atorvastatin for rebleeding in cerebral cavernous malformations (AT CASH EPOC): a phase 1/2a, randomised placebo-controlled trial. Issam Awad, et al. Lancet Neurology.

Issam Awad and colleagues from the Department of Neurological Surgery assessed the safety and efficacy of atorvastatin on rebleeding in patients with cerebral cavernous malformations (CCMs) after a symptomatic hemorrhage. They found that for people with symptomatic hemorrhage caused by CCMs, atorvastatin did not affect the mean change in lesional iron deposition on brain MRI over 2 years when compared with placebo. The trial was conceived and executed at UChicago, based on preclinical bench research and biomarker validations led by the team over more than a decade.
 
How scientists and institutions should respond. Ran Blekhman. ELife.
 
Bringing everyone to the table: expanding the menopause conversation to include trans and gender diverse people. Monica Christmas, Martha Hickey. Menopause.
 
Ethics in the Age of Consortia. Kate Keenan. JAMA Pediatrics.
 
Immunoglobulin A controls intestinal virus colonization to preserve immune homeostasis. Wioletta Lisicka, Zachary M. Earley, Joseph J. Sifakis, Steven A. Erickson, Jonathan R. Mattingly, Samantha Riesenfeld, et al. Cell Host & Microbe.
 
The genesis of paleogenetics. Maanasa Raghavan. Nature Reviews Genetics.
 
Rationale for Investigation of Neoadjuvant Chemoimmunotherapy Before Chemoradiation in Unresectable Stage III Non-Small Cell Lung Cancer. Rajat Thawani, Christine M. Bestvina, Everett E. Vokes, Aditya Juloori. Journal of Clinical Oncology.
 

GOT NEWS TO SHARE?

Send science and research news to our team to be considered for future editions.
 

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